Official answer by Drugs.com Mucinex D is (guaifenesin and pseudoephedrine) is an expectorant/nasal decongestant combination, and Mucinex DM (guaifenesin and dextromethorphan) is an expectorant/cough suppressant combination. Mucinex D and Mucinex DM both contain the expectorant guaifenesin (which is contained as a single ingredient in Mucinex ).
Mucinex and Mucinex DM both contain an expectorant that helps loosen mucus. Mucinex DM
Fact Checked Mucinex DM is an over-the-counter (OTC) combination medication that relieves cough and chest congestion caused by the common cold, flu, and allergies. Each tablet combines dextromethorphan hydrobromide, a cough suppressant, with guaifenesin, a drug that loosens mucus and bronchial secretions in the lungs.
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